Smultron a text editor with a Lisp backend (no, not that one) which has now replaced SubEthaEdit as my favorite editor (at least, for non-collaborative editing)
TouchStream LP (Dvorak) indispensible, and so much more efficient than mice or trackballs or trackpads; especially since I suffer from RSI
Privoxy HTTP/HTTPS filtering proxy - get rid of ads, cookies, some malicious Javascript